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KMID : 0388219940010010091
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Journal of the Korean Rheumatism Association
1994 Volume.1 No. 1 p.91 ~ p.97
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Systemic Lupus Erythematosus with Involvement of Liver and Central Nervous System(A Case Report)
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Abstract
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We report a pateint with CNS-SLE who initially manifested liver involvement. We emphasize the difficulty in differentiaitng autoimmune hepatitis and hepatic involvement of SLE, clinically, immunologically, radiologically, pathologically.
Neuropsychiatric disorders casued by lupus activity occur during the course of the illness in 35~75% of patients with SLE. It is a poor prognostic sign and frequent cause of death in lupus patients. Recently some evidence suggest that
single-photon-emission computed tomography(SPECT) of brain is useful for detecting abnormalities of regional cerebral blood flow in patients with CNS lupus. We were able to conclude that CNS symptoms in this patient were due to CNS involovement
of
SLE.
Although MRI of brain showed some high signal intensity in parehchyme of brain, this findings were said to be common in chronic liver diseases. In this situdation we think that SPECT of brain might be performed for differentiation of the cause of
CNS
symptoms in SLE patient with chronic liver disease.
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KEYWORD
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